Here I am infusing a custom cocktail of Salmon Sperm (PDRN) probably the BEST choice of all because it leaves you glowing not showing.
I’ve tried it on myself and WOW. I can tell such a difference in my skin.
Then I’m going to take some salmon sperm, which I don’t know about you all, but I trust a lot more than humans.
A closer look
Infusion Facial. The details.
All these growth factors are going into my old tired cells that are stressed out and annoyed and getting them to get up.
I’m trying to get my cells to do something instead of just sit there. Instead of filling them up every six months.
It’s science, it’s skincare, and it works. Don’t let the name scare you away from your best skin yet!
What PDRN is
Polydeoxyribonucleotide: short pieces of DNA, purified from salmon. No cells, no sperm — the DNA fragments, and nothing else. Your own cells read them as a signal to repair. The one I use is Toskani’s, from a Barcelona laboratory that began as a pharmacy in 1953.
What it does in the skin
The fragments switch on a receptor on your cells (adenosine A2A) that turns inflammation down and turns repair up: more collagen, more elastin, better blood supply. They also hand the cell the raw material it needs to build new DNA. That is the whole mechanism, and it is why the studies keep finding the same things — hydration, elasticity, texture.
Why it goes in with needles
PDRN is a big molecule. On top of unbroken skin it stays on top. So I put it in with SkinPen: the microneedling opens thousands of channels for a few minutes, and the salmon DNA goes in while they are open. This is why a serum from a bottle and this treatment are not the same thing.
Where
Face. Face and neck. Face, neck and chest. The eyes on their own, for crepey lids and the shadow under them. The scalp, for thinning hair. And as an add-on right after Moxi or BBL, when the skin is already open and asking for it.
What it is not
It is not an injection. The injectable salmon DNA you see in Korea (Rejuran and its cousins) is not FDA-approved in the United States, and nobody here is injecting it. It is not a filler: nothing is added, nothing is plumped. It is your own skin doing the work, faster.
A few questions.
The things people ask.
Is there really sperm in it?
No. PDRN is DNA purified from salmon; the cells are long gone. The name is a marketing accident that stuck. The science underneath it is thirty years old and mostly Italian and Korean.
It’s science, it’s skincare, and it works. Don’t let the name scare you away from your best skin yet!
What do the studies actually show?
Early studies suggest benefits, but the product and how it is delivered matter. A 2026 review included seven small trials involving 183 people across skin rejuvenation, scars and wound healing. The treatments varied, and larger studies are needed. Read the review.
A separate study of 27 people compared injected PN with injected hyaluronic acid around the eyes. PN performed better on some skin measurements, but overall aesthetic ratings did not differ significantly. That was a different treatment from topical PDRN used with microneedling, so those results do not establish what this facial will do. Read the periocular trial.
Does it hurt? What is the downtime?
SkinPen with numbing cream is a scratch, not a pain. Pink for a day, sometimes two; makeup the next morning. It is a lunch-hour treatment.
Just like putting on makeup but with needles.
How many do I need?
One shows. A series of three, a month apart, is what the studies used and what I do for a real change; then one whenever you want the glow back.
Is it better than exosomes or PRP?
It is cleaner. PRP is your own blood, spun; exosomes are somebody else’s cells, processed. PDRN is a defined molecule from a fish, and I know exactly what is in the bottle.
And I think it’s safer than exosomes because you never know where those exosomes have been or who they… whose blood they were swimming around in.
Can I do it after a laser?
Yes — that is the best time. After Moxi or BBL the skin is already open and inflamed, which is exactly what PDRN is for. Ask for it as the add-on.
What does it cost?
Face, face and neck, face-neck-chest, eyes alone, scalp, or the add-on after a laser. Every price is on the booking page, and the price you see is the price.
Which PDRN is it?
Toskani Lumicen, from Barcelona — a 3% PDRN complex with low- and medium-weight hyaluronic acid, made for professional use by a pharmaceutical laboratory that has made mesotherapy formulas since 1994, in ISO-certified manufacturing. I know exactly what is in the bottle, and it went on my own face before it went on anyone else’s.